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Sesame Oil-Based Nanostructured Lipid Carriers of Nicergoline, Intranasal Delivery System for Brain Targeting of Synergistic Cerebrovascular Protection

Nicergoline (NIC) is a semisynthetic ergot alkaloid derivative applied for treatment of dementia and other cerebrovascular disorders. The efficacy of sesame oil to slow and reverse the symptoms of neurodegenerative cognitive disorders has been proven. This work aimed to formulate and optimize sesame...

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Detalles Bibliográficos
Autores principales: Abourehab, Mohammed A. S., Khames, Ahmed, Genedy, Samar, Mostafa, Shahin, Khaleel, Mohammad A., Omar, Mahmoud M., El Sisi, Amani M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072759/
https://www.ncbi.nlm.nih.gov/pubmed/33921796
http://dx.doi.org/10.3390/pharmaceutics13040581