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Sesame Oil-Based Nanostructured Lipid Carriers of Nicergoline, Intranasal Delivery System for Brain Targeting of Synergistic Cerebrovascular Protection
Nicergoline (NIC) is a semisynthetic ergot alkaloid derivative applied for treatment of dementia and other cerebrovascular disorders. The efficacy of sesame oil to slow and reverse the symptoms of neurodegenerative cognitive disorders has been proven. This work aimed to formulate and optimize sesame...
Autores principales: | Abourehab, Mohammed A. S., Khames, Ahmed, Genedy, Samar, Mostafa, Shahin, Khaleel, Mohammad A., Omar, Mahmoud M., El Sisi, Amani M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072759/ https://www.ncbi.nlm.nih.gov/pubmed/33921796 http://dx.doi.org/10.3390/pharmaceutics13040581 |
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