Citric Acid Cycle Metabolites Predict Infarct Size in Pigs Submitted to Transient Coronary Artery Occlusion and Treated with Succinate Dehydrogenase Inhibitors or Remote Ischemic Perconditioning

Succinate dehydrogenase (SDH) inhibition with malonate during reperfusion reduced myocardial infarction in animals, whereas its endogenous substrate, succinate, is detected in plasma from STEMI patients. We investigated whether protection by SDH inhibition is additive to that of remote ischemic perc...

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Detalles Bibliográficos
Autores principales: Consegal, Marta, Núñez, Norberto, Barba, Ignasi, Benito, Begoña, Ruiz-Meana, Marisol, Inserte, Javier, Ferreira-González, Ignacio, Rodríguez-Sinovas, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072915/
https://www.ncbi.nlm.nih.gov/pubmed/33923786
http://dx.doi.org/10.3390/ijms22084151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072915/
https://www.ncbi.nlm.nih.gov/pubmed/33923786
http://dx.doi.org/10.3390/ijms22084151

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