Introduction of Cysteines in the Stalk Domain of Recombinant Influenza Virus N1 Neuraminidase Enhances Protein Stability and Immunogenicity in Mice

Influenza virus surface glycoproteins represent the main targets of the immune system during infection and vaccination. Current influenza virus vaccines rely mostly on the hemagglutinin, requiring a close match between the vaccine and circulating strains. Recently, the neuraminidase (NA) has become...

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Detalles Bibliográficos
Autores principales: Strohmeier, Shirin, Carreño, Juan Manuel, Brito, Ruhi Nichalle, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072926/
https://www.ncbi.nlm.nih.gov/pubmed/33921722
http://dx.doi.org/10.3390/vaccines9040404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072926/
https://www.ncbi.nlm.nih.gov/pubmed/33921722
http://dx.doi.org/10.3390/vaccines9040404

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