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Meropenem Stability in Human Plasma at −20 °C: Detailed Assessment of Degradation

There are concerns about the stability of meropenem in plasma samples, even when frozen at −20 °C. Previous smaller studies suggested significant degradation of meropenem at −20 °C after 3–20 days. However, in several recent clinical studies, meropenem plasma samples were still stored at −20 °C, or...

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Detalles Bibliográficos
Autores principales: Gijsen, Matthias, Filtjens, Benjamin, Annaert, Pieter, Armoudjian, Yeghig, Debaveye, Yves, Wauters, Joost, Slaets, Peter, Spriet, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072937/
https://www.ncbi.nlm.nih.gov/pubmed/33923550
http://dx.doi.org/10.3390/antibiotics10040449