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Favorable Effects of Voriconazole Trough Concentrations Exceeding 1 μg/mL on Treatment Success and All-Cause Mortality: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis examined the optimal trough concentration of voriconazole for adult patients with invasive fungal infections. We used stepwise cutoffs of 0.5–2.0 μg/mL for efficacy and 3.0–6.0 μg/mL for safety. Studies were included if they reported the rates of all-cause mo...

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Detalles Bibliográficos
Autores principales: Hanai, Yuki, Hamada, Yukihiro, Kimura, Toshimi, Matsumoto, Kazuaki, Takahashi, Yoshiko, Fujii, Satoshi, Nishizawa, Kenji, Miyazaki, Yoshitsugu, Takesue, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072959/
https://www.ncbi.nlm.nih.gov/pubmed/33923727
http://dx.doi.org/10.3390/jof7040306