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The Challenges and Strategies of Antisense Oligonucleotide Drug Delivery
Antisense oligonucleotides (ASOs) are used to selectively inhibit the translation of disease-associated genes via Ribonuclease H (RNaseH)-mediated cleavage or steric hindrance. They are being developed as a novel and promising class of drugs targeting a wide range of diseases. Despite the great pote...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8072990/ https://www.ncbi.nlm.nih.gov/pubmed/33923688 http://dx.doi.org/10.3390/biomedicines9040433 |