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Prognostic value of absolute quantification of mutated KRAS in circulating tumour DNA in lung adenocarcinoma patients prior to therapy

Droplet digital polymerase chain reaction (ddPCR) is a highly sensitive and accurate method for quantification of nucleic acid sequences. We used absolute quantification of mutated v‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homology gene (KRAS) by ddPCR to investigate the prognostic role of mutate...

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Detalles Bibliográficos
Autores principales: Wahl, Sissel Gyrid Freim, Dai, Hong Yan, Emdal, Elisabeth F, Ottestad, Anine L, Dale, Vibeke G, Richardsen, Elin, Halvorsen, Tarje O, Grønberg, Bjørn Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073004/
https://www.ncbi.nlm.nih.gov/pubmed/33502820
http://dx.doi.org/10.1002/cjp2.200