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Antibodies to Citrullinated Proteins (ACPA) Associate with Markers of Osteoclast Activation and Bone Destruction in the Bone Marrow of Patients with Rheumatoid Arthritis

Normalizing bone metabolism is a challenge in rheumatoid arthritis (RA). Studies in mice suggest that anti-citrullinated protein antibodies (ACPAs) can trigger osteoclast activation and bone resorption in the bone marrow. However, data on the presence and role of ACPAs in human bone marrow are scarc...

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Detalles Bibliográficos
Autores principales: Kurowska, Weronika, Slowinska, Iwona, Krogulec, Zbigniew, Syrowka, Piotr, Maslinski, Wlodzimierz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073027/
https://www.ncbi.nlm.nih.gov/pubmed/33921836
http://dx.doi.org/10.3390/jcm10081778