Mangiferin Inhibits Apoptosis in Doxorubicin-Induced Vascular Endothelial Cells via the Nrf2 Signaling Pathway

Doxorubicin increases endothelial permeability, hence increasing cardiomyocytes’ exposure to doxorubicin (DOX) and exposing myocytes to more immediate damage. Reactive oxygen species are major effector molecules of doxorubicin’s activity. Mangiferin (MGN) is a xanthone derivative that consists of C-...

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Detalles Bibliográficos
Autores principales: Ismail, Mohammad Bani, Rajendran, Peramaiyan, AbuZahra, Hamad Mohammed, Veeraraghavan, Vishnu Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073066/
https://www.ncbi.nlm.nih.gov/pubmed/33923922
http://dx.doi.org/10.3390/ijms22084259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073066/
https://www.ncbi.nlm.nih.gov/pubmed/33923922
http://dx.doi.org/10.3390/ijms22084259

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