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Multi-Enzymatic Cascades in the Synthesis of Modified Nucleosides: Comparison of the Thermophilic and Mesophilic Pathways

A comparative study of the possibilities of using ribokinase → phosphopentomutase → nucleoside phosphorylase cascades in the synthesis of modified nucleosides was carried out. Recombinant phosphopentomutase from Thermus thermophilus HB27 was obtained for the first time: a strain producing a soluble...

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Detalles Bibliográficos
Autores principales: Fateev, Ilja V., Kostromina, Maria A., Abramchik, Yuliya A., Eletskaya, Barbara Z., Mikheeva, Olga O., Lukoshin, Dmitry D., Zayats, Evgeniy A., Berzina, Maria Ya., Dorofeeva, Elena V., Paramonov, Alexander S., Kayushin, Alexey L., Konstantinova, Irina D., Esipov, Roman S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073115/
https://www.ncbi.nlm.nih.gov/pubmed/33923608
http://dx.doi.org/10.3390/biom11040586