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Interferon Gamma Inhibits Equine Herpesvirus 1 Replication in a Cell Line-Dependent Manner

The sole equine herpesvirus 1 (EHV-1) immediate-early protein (IEP) is essential for viral replication by transactivating viral immediate-early (IE), early (E), and late (L) genes. Here, we report that treatment of mouse MH-S, equine NBL6, and human MRC-5 cells with 20 ng/mL of IFN-γ reduced EHV-1 y...

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Detalles Bibliográficos
Autores principales: Kim, Seong K., Shakya, Akhalesh K., O’Callaghan, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073143/
https://www.ncbi.nlm.nih.gov/pubmed/33923733
http://dx.doi.org/10.3390/pathogens10040484