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Temozolomide Induces the Acquisition of Invasive Phenotype by O6-Methylguanine-DNA Methyltransferase (MGMT)(+) Glioblastoma Cells in a Snail-1/Cx43-Dependent Manner

Glioblastoma multiforme (GBM) recurrences after temozolomide (TMZ) treatment result from the expansion of drug-resistant and potentially invasive GBM cells. This process is facilitated by O6-Methylguanine-DNA Methyltransferase (MGMT), which counteracts alkylating TMZ activity. We traced the expansio...

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Detalles Bibliográficos
Autores principales:	Kochanowski, Paweł, Catapano, Jessica, Pudełek, Maciej, Wróbel, Tomasz, Madeja, Zbigniew, Ryszawy, Damian, Czyż, Jarosław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073161/ https://www.ncbi.nlm.nih.gov/pubmed/33923767 http://dx.doi.org/10.3390/ijms22084150

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