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Effects of Environmental Conditions on Nephron Number: Modeling Maternal Disease and Epigenetic Regulation in Renal Development

A growing body of evidence suggests that low nephron numbers at birth can increase the risk of chronic kidney disease or hypertension later in life. Environmental stressors, such as maternal malnutrition, medication and smoking, can influence renal size at birth. Using metanephric organ cultures to...

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Detalles Bibliográficos
Autores principales: Fuhrmann, Lars, Lindner, Saskia, Hauser, Alexander-Thomas, Höse, Clemens, Kretz, Oliver, Cohen, Clemens D., Lindenmeyer, Maja T., Sippl, Wolfgang, Jung, Manfred, Huber, Tobias B., Wanner, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073167/
https://www.ncbi.nlm.nih.gov/pubmed/33923831
http://dx.doi.org/10.3390/ijms22084157