Supervised enhancer prediction with epigenetic pattern recognition and targeted validation

Enhancers are important noncoding elements, but they have been traditionally hard to characterize experimentally. The development of massively parallel assays allows the characterization of large numbers of enhancers for the first time. Here, we developed a framework using Drosophila STARR-seq to cr...

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Detalles Bibliográficos
Autores principales: Sethi, Anurag, Gu, Mengting, Gumusgoz, Emrah, Chan, Landon, Yan, Koon-Kiu, Rozowsky, Joel, Barozzi, Iros, Afzal, Veena, Akiyama, Jennifer A., Plajzer-Frick, Ingrid, Yan, Chengfei, Novak, Catherine S., Kato, Momoe, Garvin, Tyler H., Pham, Quan, Harrington, Anne, Mannion, Brandon J., Lee, Elizabeth A., Fukuda-Yuzawa, Yoko, Visel, Axel, Dickel, Diane E., Yip, Kevin Y., Sutton, Richard, Pennacchio, Len A., Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073243/
https://www.ncbi.nlm.nih.gov/pubmed/32737473
http://dx.doi.org/10.1038/s41592-020-0907-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073243/
https://www.ncbi.nlm.nih.gov/pubmed/32737473
http://dx.doi.org/10.1038/s41592-020-0907-8

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