αvβ3 Integrin Expression and Mitogenic Effects by Thyroid Hormones in Chronic Lymphocytic Leukemia

Background: Chronic lymphocytic leukemia (CLL) is the most common adult leukemia. The thyroid hormones, T3 and T4, bind the αvβ3 integrin and activate phosphorylates ERK (pERK). These tumor-promoting actions were reported in a number of malignancies, but not in CLL. Methods: Primary cells from 22 CL...

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Detalles Bibliográficos
Autores principales: Abadi, Uri, Weisz, Avivit, Kidron, Dvora, Katzav, Aviva, Hercbergs, Aleck, Davis, Paul J., Ellis, Martin H., Ashur-Fabian, Osnat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073405/
https://www.ncbi.nlm.nih.gov/pubmed/33921634
http://dx.doi.org/10.3390/jcm10081766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073405/
https://www.ncbi.nlm.nih.gov/pubmed/33921634
http://dx.doi.org/10.3390/jcm10081766

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