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Phase I Trial Evaluating the Safety and Immunogenicity of Candidate TB Vaccine MVA85A, Delivered by Aerosol to Healthy M.tb-Infected Adults

The immunogenicity of the candidate tuberculosis (TB) vaccine MVA85A may be enhanced by aerosol delivery. Intradermal administration was shown to be safe in adults with latent TB infection (LTBI), but data are lacking for aerosol-delivered candidate TB vaccines in this population. We carried out a P...

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Detalles Bibliográficos
Autores principales: Riste, Michael, Marshall, Julia L., Satti, Iman, Harris, Stephanie A., Wilkie, Morven, Lopez Ramon, Raquel, Wright, Danny, Wittenberg, Rachel E., Vermaak, Samantha, Powell Doherty, Rebecca, Lawrie, Alison, Conlon, Christopher P., Cosgrove, Catherine, Gleeson, Fergus, Lipman, Marc, Moss, Paul, Perrin, Felicity, Dedicoat, Martin, Bettinson, Henry, McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073411/
https://www.ncbi.nlm.nih.gov/pubmed/33923628
http://dx.doi.org/10.3390/vaccines9040396