Cargando…

Ecklonia cava Extract and Its Derivative Dieckol Promote Vasodilation by Modulating Calcium Signaling and PI3K/AKT/eNOS Pathway in In Vitro and In Vivo Models

Nitric oxide (NO), an endothelial-derived relaxing factor synthesized by endothelial nitric oxide synthase (eNOS) in endothelial cells, enhances vasodilation by modulating vascular tone. The calcium concentration critically influences eNOS activation in endothelial cells. Thus, modulation of calcium...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yu-An, Je, Jun-Geon, Hwang, Jin, Jeon, You-Jin, Ryu, BoMi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073412/
https://www.ncbi.nlm.nih.gov/pubmed/33921856
http://dx.doi.org/10.3390/biomedicines9040438