Cargando…

Ecklonia cava Extract and Its Derivative Dieckol Promote Vasodilation by Modulating Calcium Signaling and PI3K/AKT/eNOS Pathway in In Vitro and In Vivo Models

Nitric oxide (NO), an endothelial-derived relaxing factor synthesized by endothelial nitric oxide synthase (eNOS) in endothelial cells, enhances vasodilation by modulating vascular tone. The calcium concentration critically influences eNOS activation in endothelial cells. Thus, modulation of calcium...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Yu-An, Je, Jun-Geon, Hwang, Jin, Jeon, You-Jin, Ryu, BoMi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073412/ https://www.ncbi.nlm.nih.gov/pubmed/33921856 http://dx.doi.org/10.3390/biomedicines9040438

Ejemplares similares

Effect of Dieckol, a Component of Ecklonia cava, on the Promotion of Hair Growth
por: Kang, Jung-Il, et al.
Publicado: (2012)

Anti-Melanogenesis and Photoprotective Effects of Ecklonia maxima Extract Containing Dieckol and Eckmaxol
por: Wang, Lei, et al.
Publicado: (2022)

First Evidence that Ecklonia cava-Derived Dieckol Attenuates MCF-7 Human Breast Carcinoma Cell Migration
por: Kim, Eun-Kyung, et al.
Publicado: (2015)

Diphlorethohydroxycarmalol Isolated from Ishige okamurae Exerts Vasodilatory Effects via Calcium Signaling and PI3K/Akt/eNOS Pathway
por: Lu, Yu An, et al.
Publicado: (2021)

Ecklonia cava Extract and Dieckol Attenuate Cellular Lipid Peroxidation in Keratinocytes Exposed to PM10
por: Lee, Jeong-won, et al.
Publicado: (2018)

The anti-aging properties of a human placental hydrolysate combined with dieckol isolated from Ecklonia cava
por: Jang, Su Kil, et al.
Publicado: (2015)

Anti-hyperlipidemic Effect of Polyphenol Extract (Seapolynol(™)) and Dieckol Isolated from Ecklonia cava in in vivo and in vitro Models
por: Yeo, A-Reum, et al.
Publicado: (2012)

Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava
por: Park, Ji-Young, et al.
Publicado: (2013)

Effect of Phlorofucofuroeckol A and Dieckol Extracted from Ecklonia cava on Noise-induced Hearing Loss in a Mouse Model
por: Woo, Hyunjun, et al.
Publicado: (2021)

Therapeutic Potential of Phlorotannin-Rich Ecklonia cava Extract on Methylglyoxal-Induced Diabetic Nephropathy in In Vitro Model
por: Cho, Chi-Heung, et al.
Publicado: (2022)

Shenfu Injection Promotes Vasodilation by Enhancing eNOS Activity Through the PI3K/Akt Signaling Pathway In Vitro
por: Zhu, Jinqiang, et al.
Publicado: (2020)

Dieckol, Derived from the Edible Brown Algae Ecklonia cava, Attenuates Methylglyoxal-Associated Diabetic Nephropathy by Suppressing AGE–RAGE Interaction
por: Cho, Chi-Heung, et al.
Publicado: (2023)

Marine Alga Ecklonia cava Extract and Dieckol Attenuate Prostaglandin E(2) Production in HaCaT Keratinocytes Exposed to Airborne Particulate Matter
por: Ha, Jae Won, et al.
Publicado: (2019)

Endothelial NO Production Is Mandatory for Epigallocatechin-3-Gallate–induced Vasodilation: Results From eNOS Knockout (eNOS(−/−)) Mice
por: Lorenz, Mario, et al.
Publicado: (2015)

Mitigative Effects of PFF-A Isolated from Ecklonia cava on Pigmentation in a Zebrafish Model and Melanogenesis in B16F10 Cells
por: Je, Jun-Geon, et al.
Publicado: (2022)

Dieckol, a Component of Ecklonia cava, Suppresses the Production of MDC/CCL22 via Down-Regulating STAT1 Pathway in Interferon-γ Stimulated HaCaT Human Keratinocytes
por: Kang, Na-Jin, et al.
Publicado: (2015)

Dieckol from Ecklonia cava Regulates Invasion of Human Fibrosarcoma Cells and Modulates MMP-2 and MMP-9 Expression via NF-κB Pathway
por: Zhang, Chen, et al.
Publicado: (2011)

Pyrogallol-Phloroglucinol-6,6’-Bieckol from Ecklonia cava Improved Blood Circulation in Diet-Induced Obese and Diet-Induced Hypertension Mouse Models
por: Son, Myeongjoo, et al.
Publicado: (2019)

Urinary Metabolomic Profiling Analysis and Evaluation of the Effect of Ecklonia cava Extract Intake
por: Kim, Juyeon, et al.
Publicado: (2020)

Eckol from Ecklonia cava Suppresses Immunoglobulin E-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice (Running Title: Anti-Allergic Activity of Ecklonia cava)
por: Han, Eui Jeong, et al.
Publicado: (2020)

Enhancement of Human Hair Growth Using Ecklonia cava Polyphenols
por: Shin, Hyoseung, et al.
Publicado: (2016)

Effect of eNOS polymorphisms on salbutamol evoked endothelium dependent vasodilation in South Indian healthy subjects
por: Kumar, Srinivasamurthy Suresh, et al.
Publicado: (2013)

Seapolynol Extracted from Ecklonia cava Inhibits Adipocyte Differentiation in Vitro and Decreases Fat Accumulation in Vivo
por: Jeon, Hui-Jeon, et al.
Publicado: (2015)

Slow-Binding Inhibition of Tyrosinase by Ecklonia cava Phlorotannins
por: Kim, Jang Hoon, et al.
Publicado: (2019)

Dieckol, an Algae-Derived Phenolic Compound, Suppresses UVB-Induced Skin Damage in Human Dermal Fibroblasts and Its Underlying Mechanisms
por: Wang, Lei, et al.
Publicado: (2021)

A sulfated polysaccharide of Ecklonia cava inhibits the growth of colon cancer cells by inducing apoptosis
por: Ahn, Ginnae, et al.
Publicado: (2015)

Effect of phlorotannins isolated from Ecklonia cava on angiotensin I-converting enzyme (ACE) inhibitory activity
por: Wijesinghe, W.A.J.P., et al.
Publicado: (2011)

Laxative Effects of Phlorotannins Derived from Ecklonia cava on Loperamide-Induced Constipation in SD Rats
por: Kim, Ji-Eun, et al.
Publicado: (2021)

Metabolic syndrome in rats is associated with erectile dysfunction by impairing PI3K/Akt/eNOS activity
por: Li, Rui, et al.
Publicado: (2017)

Purification and Structural Characterization of Sulfated Polysaccharides Derived from Brown Algae, Sargassum binderi: Inhibitory Mechanism of iNOS and COX-2 Pathway Interaction
por: Je, Jun-Geon, et al.
Publicado: (2021)

Matrine attenuates high‐fat diet‐induced in vivo and ox‐LDL‐induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways
por: Zhang, Song, et al.
Publicado: (2019)

(-)-Epigallocatechin-3-Gallate Inhibits eNOS Uncoupling and Alleviates High Glucose-Induced Dysfunction and Apoptosis of Human Umbilical Vein Endothelial Cells by PI3K/AKT/eNOS Pathway
por: Zhang, Zhiyong, et al.
Publicado: (2020)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Cryptotanshinone exhibits therapeutical effects on cerebral stroke through the PI3K/AKT-eNOS signaling pathway
por: Zhu, Weixin, et al.
Publicado: (2017)

Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation
por: Hohmann, Nicolas, et al.
Publicado: (2016)

Crocetin promotes angiogenesis in human endothelial cells through PI3K-Akt-eNOS signaling pathway
por: Nasirzadeh, Mahdieh, et al.
Publicado: (2019)

Baicalin Targets HSP70/90 to Regulate PKR/PI3K/AKT/eNOS Signaling Pathways
por: Hou, Yinzhu, et al.
Publicado: (2022)

Sildenafil-Induced Revascularization of Rat Hindlimb Involves Arteriogenesis through PI3K/AKT and eNOS Activation
por: Baron-Menguy, Celine, et al.
Publicado: (2022)

(-)-Epigallocatechin-3-Gallate Inhibits eNOS Uncoupling and Alleviates High Glucose-Induced Dysfunction and Apoptosis of Human Umbilical Vein Endothelial Cells by PI3K/AKT/eNOS Pathway [Corrigendum]
Publicado: (2020)

Antihypertensive Effects of IGTGIPGIW Peptide Purified from Hippocampus abdominalis: p-eNOS and p-AKT Stimulation in EA.hy926 Cells and Lowering of Blood Pressure in SHR Model
por: Lee, Hyo-Geun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i08c7ugctkb2fd9v1bfbufg46r