Human Prostate Epithelial Cells Activate the AIM2 Inflammasome upon Cellular Senescence: Role of POP3 Protein in Aging-Related Prostatic Inflammation

Increased levels of type I (T1) interferon (IFN)-inducible POP3 protein in myeloid cells inhibit activation of the AIM2 inflammasome and production of IL-1β and IL-18 proinflammatory cytokines. The AIM2 mRNA levels were significantly higher in benign prostate hyperplasia (BPH) than the normal prosta...

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Detalles Bibliográficos
Autores principales: Panchanathan, Ravichandran, Ramalingam, Vaikundamoorthy, Liu, Hongzhu, Choubey, Divaker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073538/
https://www.ncbi.nlm.nih.gov/pubmed/33923931
http://dx.doi.org/10.3390/life11040366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073538/
https://www.ncbi.nlm.nih.gov/pubmed/33923931
http://dx.doi.org/10.3390/life11040366

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