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Clusterin Deficiency Exacerbates Hyperoxia-Induced Acute Lung Injury
Exposure to high oxygen concentrations leads to generation of excessive reactive oxygen species, causing cellular injury and multiple organ dysfunctions and is associated with a high mortality rate. Clusterin (CLU) is a heterodimeric glycoprotein that mediates several intracellular signaling pathway...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073575/ https://www.ncbi.nlm.nih.gov/pubmed/33921872 http://dx.doi.org/10.3390/cells10040944 |