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The Human 2-Cys Peroxiredoxins form Widespread, Cysteine-Dependent- and Isoform-Specific Protein-Protein Interactions

Redox signaling is controlled by the reversible oxidation of cysteine thiols, a post-translational modification triggered by H(2)O(2) acting as a second messenger. However, H(2)O(2) actually reacts poorly with most cysteine thiols and it is not clear how H(2)O(2) discriminates between cysteines to t...

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Detalles Bibliográficos
Autores principales: van Dam, Loes, Pagès-Gallego, Marc, Polderman, Paulien E., van Es, Robert M., Burgering, Boudewijn M. T., Vos, Harmjan R., Dansen, Tobias B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073576/
https://www.ncbi.nlm.nih.gov/pubmed/33923941
http://dx.doi.org/10.3390/antiox10040627