Estrogen Decreases Cytoskeletal Organization by Forming an ERα/SHP2/c-Src Complex in Osteoclasts to Protect against Ovariectomy-Induced Bone Loss in Mice

Loss of ovarian function is closely related to estrogen (E(2)) deficiency, which is responsible for increased osteoclast (OC) differentiation and activity. We aimed to investigate the action mechanism of E(2) to decrease bone resorption in OCs to protect from ovariectomy (OVX)-induced bone loss in m...

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Detalles Bibliográficos
Autores principales: Park, Hyun-Jung, Gholam-Zadeh, Malihatosadat, Yoon, Sun-Young, Suh, Jae-Hee, Choi, Hye-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073670/
https://www.ncbi.nlm.nih.gov/pubmed/33920630
http://dx.doi.org/10.3390/antiox10040619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073670/
https://www.ncbi.nlm.nih.gov/pubmed/33920630
http://dx.doi.org/10.3390/antiox10040619

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