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Estrogen Decreases Cytoskeletal Organization by Forming an ERα/SHP2/c-Src Complex in Osteoclasts to Protect against Ovariectomy-Induced Bone Loss in Mice
Loss of ovarian function is closely related to estrogen (E(2)) deficiency, which is responsible for increased osteoclast (OC) differentiation and activity. We aimed to investigate the action mechanism of E(2) to decrease bone resorption in OCs to protect from ovariectomy (OVX)-induced bone loss in m...
Autores principales: | Park, Hyun-Jung, Gholam-Zadeh, Malihatosadat, Yoon, Sun-Young, Suh, Jae-Hee, Choi, Hye-Seon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073670/ https://www.ncbi.nlm.nih.gov/pubmed/33920630 http://dx.doi.org/10.3390/antiox10040619 |
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