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Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate

Pancreatic cancer cells (PDACs) are more susceptible to an oxidative insult than normal cells, resulting in greater cytotoxicity upon exposure to agents that increase pro-oxidant levels. Pharmacological ascorbate (P-AscH(−)), i.e., large amounts given intravenously (IV), generates significant fluxes...

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Detalles Bibliográficos
Autores principales: Du, Juan, Carroll, Rory S., Steers, Garett J., Wagner, Brett A., O’Leary, Brianne R., Jensen, Chris S., Buettner, Garry R., Cullen, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073689/
https://www.ncbi.nlm.nih.gov/pubmed/33923601
http://dx.doi.org/10.3390/antiox10040614