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Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate
Pancreatic cancer cells (PDACs) are more susceptible to an oxidative insult than normal cells, resulting in greater cytotoxicity upon exposure to agents that increase pro-oxidant levels. Pharmacological ascorbate (P-AscH(−)), i.e., large amounts given intravenously (IV), generates significant fluxes...
Autores principales: | Du, Juan, Carroll, Rory S., Steers, Garett J., Wagner, Brett A., O’Leary, Brianne R., Jensen, Chris S., Buettner, Garry R., Cullen, Joseph J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073689/ https://www.ncbi.nlm.nih.gov/pubmed/33923601 http://dx.doi.org/10.3390/antiox10040614 |
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