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Genetic Variants in Transcription Factor Binding Sites in Humans: Triggered by Natural Selection and Triggers of Diseases

Variants of transcription factor binding sites (TFBSs) constitute an important part of the human genome. Current evidence demonstrates close links between nucleotides within TFBSs and gene expression. There are multiple pathways through which genomic sequences located in TFBSs regulate gene expressi...

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Detalles Bibliográficos
Autores principales: Tseng, Chia-Chun, Wong, Man-Chun, Liao, Wei-Ting, Chen, Chung-Jen, Lee, Su-Chen, Yen, Jeng-Hsien, Chang, Shun-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073710/
https://www.ncbi.nlm.nih.gov/pubmed/33919522
http://dx.doi.org/10.3390/ijms22084187