Anti-PD-1/PD-L1 Based Combination Immunotherapy to Boost Antigen-Specific CD8(+) T Cell Response in Hepatocellular Carcinoma

SIMPLE SUMMARY: The cytotoxic T cell response against hepatocellular carcinoma antigens is exhausted and fails in its task of deleting tumoral cells. These cells are featured by the expression of negative immune checkpoints that can be modulated to restore T cell function. The blockade of the PD-1/P...

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Detalles Bibliográficos
Autores principales: Peña-Asensio, Julia, Calvo, Henar, Torralba, Miguel, Miquel, Joaquín, Sanz-de-Villalobos, Eduardo, Larrubia, Juan-Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073815/
https://www.ncbi.nlm.nih.gov/pubmed/33923463
http://dx.doi.org/10.3390/cancers13081922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073815/
https://www.ncbi.nlm.nih.gov/pubmed/33923463
http://dx.doi.org/10.3390/cancers13081922

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