Broussochalcone A Is a Novel Inhibitor of the Orphan Nuclear Receptor NR4A1 and Induces Apoptosis in Pancreatic Cancer Cells

The orphan nuclear receptor 4A1 (NR4A1) is overexpressed in pancreatic cancer and exhibits pro-oncogenic activity, and NR4A1 silencing and treatment with its inactivators has been shown to inhibit pancreatic cancer cells and tumor growth. In this study, we identified broussochalcone A (BCA) as a new...

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Detalles Bibliográficos
Autores principales: Lee, Hyo-Seon, Kim, Soo-Hyun, Kim, Bo-Mi, Safe, Stephen, Lee, Syng-Ook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073833/
https://www.ncbi.nlm.nih.gov/pubmed/33923503
http://dx.doi.org/10.3390/molecules26082316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073833/
https://www.ncbi.nlm.nih.gov/pubmed/33923503
http://dx.doi.org/10.3390/molecules26082316

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