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RNA Expression of DNA Damage Response Genes in Muscle-Invasive Bladder Cancer: Influence on Outcome and Response to Adjuvant Cisplatin-Based Chemotherapy

Background: Perioperative cisplatin-based chemotherapy (CBC) can improve the outcome of patients with muscle-invasive bladder cancer (MIBC), but it is still to be defined which patients benefit. Mutations in DNA damage response genes (DDRG) can predict the response to CBC. The value of DDRG expressi...

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Detalles Bibliográficos
Autores principales: Herrmann, Jonas, Schmidt, Helena, Nitschke, Katja, Weis, Cleo-Aron, Nuhn, Philipp, von Hardenberg, Jost, Michel, Maurice Stephan, Erben, Philipp, Worst, Thomas Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073847/
https://www.ncbi.nlm.nih.gov/pubmed/33919527
http://dx.doi.org/10.3390/ijms22084188