Lipopolysaccharide-Enhanced Responses against Aryl Hydrocarbon Receptor in FcgRIIb-Deficient Macrophages, a Profound Impact of an Environmental Toxin on a Lupus-Like Mouse Model

Fc gamma receptor IIb (FcgRIIb) is the only inhibitory-FcgR in the FcgR family, and FcgRIIb-deficient (FcgRIIb(−/−)) mice develop a lupus-like condition with hyper-responsiveness against several stimulations. The activation of aryl hydrocarbon receptor (Ahr), a cellular environmental sensor, might a...

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Detalles Bibliográficos
Autores principales: Udompornpitak, Kanyarat, Bhunyakarnjanarat, Thansita, Charoensappakit, Awirut, Dang, Cong Phi, Saisorn, Wilasinee, Leelahavanichkul, Asada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073880/
https://www.ncbi.nlm.nih.gov/pubmed/33919603
http://dx.doi.org/10.3390/ijms22084199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073880/
https://www.ncbi.nlm.nih.gov/pubmed/33919603
http://dx.doi.org/10.3390/ijms22084199

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