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Lipopolysaccharide-Enhanced Responses against Aryl Hydrocarbon Receptor in FcgRIIb-Deficient Macrophages, a Profound Impact of an Environmental Toxin on a Lupus-Like Mouse Model
Fc gamma receptor IIb (FcgRIIb) is the only inhibitory-FcgR in the FcgR family, and FcgRIIb-deficient (FcgRIIb(−/−)) mice develop a lupus-like condition with hyper-responsiveness against several stimulations. The activation of aryl hydrocarbon receptor (Ahr), a cellular environmental sensor, might a...
Autores principales: | Udompornpitak, Kanyarat, Bhunyakarnjanarat, Thansita, Charoensappakit, Awirut, Dang, Cong Phi, Saisorn, Wilasinee, Leelahavanichkul, Asada |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073880/ https://www.ncbi.nlm.nih.gov/pubmed/33919603 http://dx.doi.org/10.3390/ijms22084199 |
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