Advantages of using graph databases to explore chromatin conformation capture experiments

BACKGROUND: High-throughput sequencing Chromosome Conformation Capture (Hi-C) allows the study of DNA interactions and 3D chromosome folding at the genome-wide scale. Usually, these data are represented as matrices describing the binary contacts among the different chromosome regions. On the other h...

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Detalles Bibliográficos
Autores principales: D’Agostino, Daniele, Liò, Pietro, Aldinucci, Marco, Merelli, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073886/
https://www.ncbi.nlm.nih.gov/pubmed/33902433
http://dx.doi.org/10.1186/s12859-020-03937-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073886/
https://www.ncbi.nlm.nih.gov/pubmed/33902433
http://dx.doi.org/10.1186/s12859-020-03937-0

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