Pharmacogenetic Polygenic Risk Score for Bronchodilator Response in Children and Adolescents with Asthma: Proof-of-Concept

Genome-wide association studies (GWAS) of response to asthma medications have primarily focused on Caucasian populations, with findings that may not be generalizable to minority populations. We derived a polygenic risk score (PRS) for response to albuterol as measured by bronchodilator response (BDR...

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Detalles Bibliográficos
Autores principales: Sordillo, Joanne E., Lutz, Sharon M., McGeachie, Michael J., Lasky-Su, Jessica, Weiss, Scott T., Celedón, Juan C., Wu, Ann Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073919/
https://www.ncbi.nlm.nih.gov/pubmed/33923870
http://dx.doi.org/10.3390/jpm11040319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073919/
https://www.ncbi.nlm.nih.gov/pubmed/33923870
http://dx.doi.org/10.3390/jpm11040319

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