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Pharmacogenetic Polygenic Risk Score for Bronchodilator Response in Children and Adolescents with Asthma: Proof-of-Concept
Genome-wide association studies (GWAS) of response to asthma medications have primarily focused on Caucasian populations, with findings that may not be generalizable to minority populations. We derived a polygenic risk score (PRS) for response to albuterol as measured by bronchodilator response (BDR...
Autores principales: | Sordillo, Joanne E., Lutz, Sharon M., McGeachie, Michael J., Lasky-Su, Jessica, Weiss, Scott T., Celedón, Juan C., Wu, Ann Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073919/ https://www.ncbi.nlm.nih.gov/pubmed/33923870 http://dx.doi.org/10.3390/jpm11040319 |
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