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Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions

It has been established that the selective α2A adrenoceptor agonist guanfacine reduces hyperactivity and improves cognitive impairment in patients with attention-deficit/hyperactivity disorder (ADHD). The major mechanisms of guanfacine are considered to involve the activation of the postsynaptic α2A...

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Detalles Bibliográficos
Autores principales: Fukuyama, Kouji, Nakano, Tomosuke, Shiroyama, Takashi, Okada, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8073983/
https://www.ncbi.nlm.nih.gov/pubmed/33923533
http://dx.doi.org/10.3390/ijms22084122