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In Silico Selection and Evaluation of Pugnins with Antibacterial and Anticancer Activity Using Skin Transcriptome of Treefrog (Boana pugnax)

In order to combat bacterial and cancer resistance, we identified peptides (pugnins) with dual antibacterial l–anticancer activity from the Boana pugnax (B. pugnax) skin transcriptome through in silico analysis. Pugnins A and B were selected owing to their high similarity to the DS4.3 peptide, which...

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Detalles Bibliográficos
Autores principales: Liscano, Yamil, Medina, Laura, Oñate-Garzón, Jose, Gúzman, Fanny, Pickholz, Monica, Delgado, Jean Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074116/
https://www.ncbi.nlm.nih.gov/pubmed/33919639
http://dx.doi.org/10.3390/pharmaceutics13040578