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A Highly Active Chimeric Lysin with a Calcium-Enhanced Bactericidal Activity against Staphylococcus aureus In Vitro and In Vivo

Lysins, including chimeric lysins, have recently been explored as novel promising alternatives to failing antibiotics in treating multi-drug resistant (MDR) pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). Herein, by fusing the CHAP (cysteine, histidine-dependent amidohydrola...

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Detalles Bibliográficos
Autores principales: Li, Xiaohong, Wang, Shujuan, Nyaruaba, Raphael, Liu, Huan, Yang, Hang, Wei, Hongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074178/
https://www.ncbi.nlm.nih.gov/pubmed/33921682
http://dx.doi.org/10.3390/antibiotics10040461