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Accurate Quantification of AAV Vector Genomes by Quantitative PCR

The ability to accurately determine the dose of an adeno-associated viral (AAV) therapeutic vector is critical to the gene therapy process. Quantitative PCR (qPCR) is one of the common methods to quantify the AAV vector titre, but different variables can lead to inconsistent results. The aim of this...

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Detalles Bibliográficos
Autores principales: Martinez-Fernandez de la Camara, Cristina, McClements, Michelle E., MacLaren, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074223/
https://www.ncbi.nlm.nih.gov/pubmed/33921790
http://dx.doi.org/10.3390/genes12040601