Melatonin Protects against the Side-Effects of 5-Fluorouracil on Hippocampal Neurogenesis and Ameliorates Antioxidant Activity in an Adult Rat Hippocampus and Prefrontal Cortex

Melatonin is an endogenous hormone that exhibits antioxidant functions and neuroprotective effects. The hippocampus and the prefrontal cortex (PFC) play an important role linked to working memory. 5-fluorouracil (5-FU) can induce oxidative stress and reduce neurogenesis in the subgranular zone (SGZ)...

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Detalles Bibliográficos
Autores principales: Suwannakot, Kornrawee, Sritawan, Nataya, Prajit, Ram, Aranarochana, Anusara, Sirichoat, Apiwat, Pannangrong, Wanassanun, Wigmore, Peter, Welbat, Jariya Umka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074234/
https://www.ncbi.nlm.nih.gov/pubmed/33923672
http://dx.doi.org/10.3390/antiox10040615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074234/
https://www.ncbi.nlm.nih.gov/pubmed/33923672
http://dx.doi.org/10.3390/antiox10040615

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