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Cold-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β production
BACKGROUND: Gout is an autoinflammatory disease driven by interleukin-1 (IL-1) induction in response to uric acid crystals. IL-1β production is dependent on inflammasome activation, which requires a priming signal, followed by an activating signal. The cold-inducible RNA-binding protein (CIRP) has b...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074240/ https://www.ncbi.nlm.nih.gov/pubmed/33902703 http://dx.doi.org/10.1186/s13075-021-02508-9 |