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Cold-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β production

BACKGROUND: Gout is an autoinflammatory disease driven by interleukin-1 (IL-1) induction in response to uric acid crystals. IL-1β production is dependent on inflammasome activation, which requires a priming signal, followed by an activating signal. The cold-inducible RNA-binding protein (CIRP) has b...

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Detalles Bibliográficos
Autores principales:	Fujita, Yuya, Yago, Toru, Matsumoto, Haruki, Asano, Tomoyuki, Matsuoka, Naoki, Temmoku, Jumpei, Sato, Shuzo, Yashiro-Furuya, Makiko, Suzuki, Eiji, Watanabe, Hiroshi, Kawakami, Atsushi, Migita, Kiyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074240/ https://www.ncbi.nlm.nih.gov/pubmed/33902703 http://dx.doi.org/10.1186/s13075-021-02508-9

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