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Fibroblast MMP14-Dependent Collagen Processing Is Necessary for Melanoma Growth

SIMPLE SUMMARY: Matrix metalloproteinases (MMPs) were considered as targets for the treatment of various cancers. However, initial trials using broad inhibitors to MMPs have failed, partly attributed to the contrasting functions of these proteases acting as tumor promoters and suppressors, among oth...

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Detalles Bibliográficos
Autores principales: Pach, Elke, Brinckmann, Jürgen, Rübsam, Matthias, Kümper, Maike, Mauch, Cornelia, Zigrino, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074311/
https://www.ncbi.nlm.nih.gov/pubmed/33924099
http://dx.doi.org/10.3390/cancers13081984