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Mineralocorticoid Receptor Antagonists Eplerenone and Spironolactone Modify Adrenal Cortex Morphology and Physiology

Mineralocorticoid receptor antagonists (MRAs) are a class of anti-hypertensive drugs that act by blocking aldosterone action. The aim of this study was to evaluate whether the MRAs spironolactone and eplerenone influence adrenal cortical physiology and morphology. Spontaneous hypertensive rats (SHR,...

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Detalles Bibliográficos
Autores principales: Pereira, Sofia S., Carvalho, Liliana, Costa, Madalena M., Melo, Armindo, Ferreira, Isabel M. P. L. V. O., Gomez-Sanchez, Celso E., Monteiro, Mariana P., Vinson, Gavin, Pignatelli, Duarte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074383/
https://www.ncbi.nlm.nih.gov/pubmed/33924172
http://dx.doi.org/10.3390/biomedicines9040441