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Interleukin-1 blockade with RPH-104 in patients with acute ST-elevation myocardial infarction: study design and rationale
BACKGROUND: Myocardial injury of ST-segment elevation myocardial infarction (STEMI) initiates an intense inflammatory response that contributes to further damage and is a predictor of increased risk of death or heart failure (HF). Interleukin-1 (IL-1) is a key mediator of local and systemic inflamma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074403/ https://www.ncbi.nlm.nih.gov/pubmed/33902621 http://dx.doi.org/10.1186/s12967-021-02828-z |