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Inhibition of retinoic acid receptor α phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3

BACKGROUND: Retinoids are promising agents in the treatment of different types of neoplasia including estrogen receptor-positive breast cancers, whereas refractoriness/low sensitivity is observed in triple-negative breast cancer (TNBC) subtype. However, the reason for these diverse retinoid-sensitiv...

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Detalles Bibliográficos
Autores principales: Lou, Siyue, Gao, Hang, Hong, Huanwu, Zhu, Zhihui, Zhao, Huajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074416/
https://www.ncbi.nlm.nih.gov/pubmed/33902658
http://dx.doi.org/10.1186/s13046-021-01941-7