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O-GlcNAcylation protein disruption by Thiamet G promotes changes on the GBM U87-MG cells secretome molecular signature

Glioblastoma (GBM) is a grade IV glioma highly aggressive and refractory to the therapeutic approaches currently in use. O-GlcNAcylation plays a key role for tumor aggressiveness and progression in different types of cancer; however, experimental evidence of its involvement in GBM are still lacking....

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Detalles Bibliográficos
Autores principales: Oliveira-Nunes, Maria Cecilia, Julião, Glaucia, Menezes, Aline, Mariath, Fernanda, Hanover, John A., Evaristo, Joseph Albert Medeiros, Nogueira, Fábio César Sousa, Dias, Wagner Barbosa, de Abreu Pereira, Denise, Carneiro, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074421/
https://www.ncbi.nlm.nih.gov/pubmed/33902430
http://dx.doi.org/10.1186/s12014-021-09317-x