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O-GlcNAcylation protein disruption by Thiamet G promotes changes on the GBM U87-MG cells secretome molecular signature
Glioblastoma (GBM) is a grade IV glioma highly aggressive and refractory to the therapeutic approaches currently in use. O-GlcNAcylation plays a key role for tumor aggressiveness and progression in different types of cancer; however, experimental evidence of its involvement in GBM are still lacking....
Autores principales: | Oliveira-Nunes, Maria Cecilia, Julião, Glaucia, Menezes, Aline, Mariath, Fernanda, Hanover, John A., Evaristo, Joseph Albert Medeiros, Nogueira, Fábio César Sousa, Dias, Wagner Barbosa, de Abreu Pereira, Denise, Carneiro, Katia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074421/ https://www.ncbi.nlm.nih.gov/pubmed/33902430 http://dx.doi.org/10.1186/s12014-021-09317-x |
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