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Scalable production and application of Pichia pastoris whole cell catalysts expressing human cytochrome P450 2C9

BACKGROUND: Currently, the numerous and versatile applications in pharmaceutical and chemical industry make the recombinant production of cytochrome P450 enzymes (CYPs) of great biotechnological interest. Accelerating the drug development process by simple, quick and scalable access of human drug me...

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Detalles Bibliográficos
Autores principales: Garrigós-Martínez, Javier, Weninger, Astrid, Montesinos-Seguí, José Luis, Schmid, Christian, Valero, Francisco, Rinnofner, Claudia, Glieder, Anton, Garcia-Ortega, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074423/
https://www.ncbi.nlm.nih.gov/pubmed/33902608
http://dx.doi.org/10.1186/s12934-021-01577-4