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Synthesis of oxadiazole-2-oxide derivatives as potential drug candidates for schistosomiasis targeting SjTGR

BACKGROUND: Schistosomiasis is a chronic parasitic disease that affects millions of people’s health worldwide. Because of the increasing drug resistance to praziquantel (PZQ), which is the primary drug for schistosomiasis, developing new drugs to treat schistosomiasis is crucial. Oxadiazole-2-oxides...

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Detalles Bibliográficos
Autores principales: Li, Gongming, Guo, Qingqing, Feng, Chao, Chen, Huan, Zhao, Wenjiao, Li, Shu, Hong, Yang, Sun, Dequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074465/
https://www.ncbi.nlm.nih.gov/pubmed/33902686
http://dx.doi.org/10.1186/s13071-021-04634-4